Data edition of
Residue An evidence-graded reference for peptide science

MOTS-c clinical trials

Every study registered on ClinicalTrials.gov that lists MOTS-c as an intervention, as of the data edition — what is being tested, in whom, by whom, and how far it has got.

Registered studies
5
Active or recruiting
4
Completed
0
With posted results
0
Planned or actual enrollment
36,468participants, summed
Registered studies of MOTS-c by phase and status
PhaseStudiesBreakdown
Phase 2 1
0 completed, 1 active or recruiting, 0 stopped, 0 other
Not applicable 1
0 completed, 1 active or recruiting, 0 stopped, 0 other
Observational 3
0 completed, 2 active or recruiting, 0 stopped, 1 other
Figure 1. 5 studies on ClinicalTrials.gov match the registry search MOTS-c. Multi-phase studies are counted at their highest phase. Open the full trial feed

Conditions studied

  1. Insulin Resistance2
  2. Hearing Loss1
  3. Diabetes1
  4. Clopidogrel Resistance1
  5. Amyloid1
  6. Prediabetes1
  7. Overweight/Obesity1
  8. Diabetes Mellitus, Type 21
  9. Kidney Disease, End-Stage1
  10. Kidney Transplant1
  11. Kidney1
  12. Kidney Disease1

Lead sponsors

  1. University of Athens2
  2. Affiliated Hospital of Nantong University1
  3. Hudson Biotech1
  4. University of Gaziantep1

The registry, study by study

Registration is not evidence of benefit; many registered studies never publish. Status and dates are as reported by sponsors to ClinicalTrials.gov.

Status
Phase

5 shown

Registered studies of MOTS-c
StudyPhaseStatusStartnSponsor
NCT07678073Comparison of the Effects of General Anesthesia and Combined Spinal-Epidural Anesthesia on Ferroptosis, Humanin and MOTS-c Levels in Renal Transplantation N/A Recruiting Mar 2026 68 University of Gaziantep
NCT07505745MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity Phase 2 Recruiting Feb 2026 120 Hudson Biotech
NCT03878706The Cardiovascular Effect of GLP-1 Agonist, SGLT2 Inhibitor and Their Combination Observational Recruiting Nov 2017 240 University of Athens
NCT06133946Cohort Of DEafness-gene Screening Observational Active, not recruiting Jan 2016 35,920 Affiliated Hospital of Nantong University
NCT04027712Platelet Reactivity, B-amyloid, MOTS-c and Mortality of Type II Diabetics With CAD Observational Unknown status Jan 2014 120 University of Athens

Run this search on ClinicalTrials.gov → Query term: MOTS-c